产品名称：花生四烯酸-d8
英文名称：Arachidonic Acid-d8
规格或纯度：A solution in methyl acetate
运输条件：超低温冰袋运输
在5、6、8、9、11、12、14和15位含有八个氘原子。拟用作通过GC或LC质谱法定量花生四烯酸的内标。花生四烯酸是所有白三烯，前列腺素和血栓烷的必需脂肪酸和前体。几乎所有的细胞花生四烯酸都在膜磷脂中被酯化，在那里它的存在通过多种相互连接的途径受到严格的调控。游离花生四烯酸是类二十烷酸第二信使生物合成的瞬时关键底物。受体刺激的游离花生四烯酸的释放，代谢和重新更新都是细胞信号转导和炎症的重要方面。
Contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. Intended for use as an internal standard for the quantification of arachidonic acid by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all leukotrienes, prostaglandins, and thromboxanes. Almost all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-update of free arachidonate are all important aspects of cell signaling and inflammation.
CAS编号：69254-37-1
沸点：57° C
溶解性：Soluble in water (1.7 mg/ml at 25.0° C), ethanol (~100 mg/ml), DMSO (~100 mg/ml), DMF (~100 mg/ml), and 0.1M Na2CO3.
储存温度-20°C储存
分子量：312.52
分子式：C20H24D8O2
Smiles：[2H]/C(=C(\\\\[2H])/C/C(=C(/[2H])\\\\C/C(=C(/[2H])\\\\C/C(=C(/[2H])\\\\CCCC(=O)O)/[2H])/[2H])/[2H])/CCCCC
PubChem CID：3246804
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