产品名称：ω-3花生四烯酸
英文名称：ω-3 Arachidonic Acid
英文别名：8Z,11Z,14Z,17Z-eicosatetraenoic acid; ω-3 AA
规格或纯度：A solution in ethanol,≥95%
运输条件：超低温冰袋运输
ω-3花生四烯酸是一种稀有的PUFA，存在于饮食中，微量。已知ω-3脂肪酸对于婴儿发育必不可少，可预防心脏病，高血压，血栓形成以及自身免疫和炎性疾病。在人类细胞培养物中，ω-3花生四烯酸已显示出抑制花生四烯酰辅酶A合成酶（K | i | = 14μM）的作用。另外，已显示抑制小牛脑提取物中的花生四烯酰辅酶A合成酶（IC | 50 |约为5μM）。
ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 fatty acids are known to be essential for infant development and protect against heart disease, hypertension, thrombosis, and autoimmune and inflammatory disorders. In human cell cultures, ω-3 arachidonic acid has been shown to inhibit arachidonoyl-CoA synthetase (K|i|= 14 μM). Additionally, it has been shown to inhibit arachidonoyl-CoA synthetase in calf brain extracts (IC|50|value of about 5μM).
CAS编号：24880-40-8
折光率：n20D1.50 (Predicted)
熔点：-144.0° C
沸点：78-80° C
溶解性：Soluble in water (1.7 mg/ml at 25° C), 0.1 M Na2CO3, ethanol, DMSO (~100 mg/ml), and DMF (~100 mg/ml).
储存温度-20°C储存
分子量：304.5
分子式：C₂₀H₃₂O₂
Smiles：CCCCCCCCCCC/C=C\\C=CC=CC=CC(=O)O
IC50
Arachidonoyl-CoA synthetase: IC₅₀= ~5 μM (calf brain extracts)
PubChem CID：11722594
Ki Data
Arachidonoyl-CoA synthetase: Ki= 14 μM (human platelet membranes)
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