产品名称：2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱
英文名称：2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine
英文别名：1-hexadecanoyl-2--(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; PAPC; PC(16:0/20:4(5Z,8Z,11Z,14Z))；16:0-20:4 PC
规格或纯度：≥95%
运输条件：超低温冰袋运输
2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱是在sn-1和sn-2位置包含棕榈酸和花生四烯酸的磷脂。2-花生四烯酸-1-棕榈酰-sn-甘油-3-磷酸胆碱可以天然存在于生物膜中。在体内，2-花生四烯基-1-棕榈酰基-sn-甘油-3-磷酸胆碱被氧化，其产物参与慢性炎症和血管疾病。2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱已用于氧化磷脂信号的研究。分离的人骨髓瘤细胞显示2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱水平降低。
2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that contains palmitic acid and arachidonic acid at the sn-1 and sn-2 positions. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine can be found naturally in biological membranes. In vivo, 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is oxidized, and its products are involved in chronic inflammation and vascular disease. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine has been utilized in the studies of oxidized phospholipid signaling. Isolated human myeloma cells showed decreased levels of 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine.product description：Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.参考sigma application：16:0-20:4 PC is suitable for use:in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysisin liposome preparation for the treatment of organoidas antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids参考sigam Biochemical/Physiological Effects：Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.
CAS编号：35418-58-7
溶解性：Soluble in chloroform.
储存温度-20°C储存
分子量：782.08
分子式：C44H80NO8P
Smiles：CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCC/C=C\\\\C/C=C\\\\C/C=C\\\\C/C=C\\\\CCCCC
PubChem CID：6438369
德尔塔热门产品推荐：DSPE-PEG-COOH，二硬脂酰磷脂酰乙醇胺-聚乙二醇-羧基MAL-PEG-NHS , 马来酰亚胺PEG活性酯DSPE-PEG-Mal、二硬脂酰磷脂酰乙醇胺-聚乙二醇-马来酰亚胺DSPE-PEG-cRGD,磷脂-聚乙二醇-靶向穿膜肽cRGD羧基化四氧化三铁纳米粒子,DMSA Coated Fe3O4 NanoparticlesCAS：59061-53-9|ZIF-8DMG-PEG2000，1,2-二肉豆蔻酰-rac-甘油-3-甲氧基聚乙二醇DSPE-PEG2000-FA，磷脂-聚乙二醇2000-叶酸DPPA，1,2-二棕榈酰-sn-甘油-3-磷酸DSPE-PEG-NH4420，二硬脂酰磷脂酰乙醇胺-聚乙二醇-氨基